Difference between revisions of "YGL209W"

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'''Description of YGL209W:''' Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter<ref name='S000043442'>Lutfiyya LL and Johnston M (1996) Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol Cell Biol 16(9):4790-7
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'''Description of YGL209W:''' Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced repression of many genes including SUC2 (invertase); binds to Mig1p-binding sites in SUC2 promoter; under low glucose conditions Mig2p relocalizes to mitochondrion, where it regulates morphology, interacts with Ups1p and antagonizes mitochondrial fission factor, Dnm1p, indicative of a role in promoting mitochondrial fusion or regulating morphology<ref name='S000148467'>Fernandez-Cid A, et al. (2012) Glucose levels regulate the nucleo-mitochondrial distribution of Mig2. Mitochondrion () {{SGDpaper|S000148467}} PMID 22353369</ref><ref name='S000043442'>Lutfiyya LL and Johnston M (1996) Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol Cell Biol 16(9):4790-7
 
  {{SGDpaper|S000043442}} PMID 8756637</ref>
 
  {{SGDpaper|S000043442}} PMID 8756637</ref>
 
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Latest revision as of 13:05, 5 April 2012

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Systematic name YGL209W
Gene name MIG2
Aliases MLZ1
Feature type ORF, Verified
Coordinates Chr VII:95858..97006
Primary SGDID S000003177


Description of YGL209W: Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced repression of many genes including SUC2 (invertase); binds to Mig1p-binding sites in SUC2 promoter; under low glucose conditions Mig2p relocalizes to mitochondrion, where it regulates morphology, interacts with Ups1p and antagonizes mitochondrial fission factor, Dnm1p, indicative of a role in promoting mitochondrial fusion or regulating morphology[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [3] [4]





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References

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  1. Fernandez-Cid A, et al. (2012) Glucose levels regulate the nucleo-mitochondrial distribution of Mig2. Mitochondrion () SGD PMID 22353369
  2. Lutfiyya LL and Johnston M (1996) Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol Cell Biol 16(9):4790-7 SGD PMID 8756637
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25

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