Difference between revisions of "YDL194W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YDL194W
Gene name SNF3
Aliases
Feature type ORF, Verified
Coordinates Chr IV:111581..114235


Description of YDL194W: Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4[1][2][3][4]




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Interactions

Regulatory

SNF3 expression is repressed by high levels of glucose, via the Snf1-Mig1 glucose repression pathway. [5] [6]




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References

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  1. Ko CH, et al. (1993) Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol Cell Biol 13(1):638-48 SGD PMID 8417358
  2. Ozcan S, et al. (1996) Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci U S A 93(22):12428-32 SGD PMID 8901598
  3. Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69 SGD PMID 10477308
  4. Vagnoli P, et al. (1998) The C-terminal domain of Snf3p mediates glucose-responsive signal transduction in Saccharomyces cerevisiae. FEMS Microbiol Lett 160(1):31-6 SGD PMID 9495009
  5. Ozcan S, et al. (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17(9):2566-73 SGD PMID 9564039
  6. submitted by Mark Johnston on 2003-03-11

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