Difference between revisions of "YJR092W"
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| − | '''Description of YJR092W:''' | + | '''Description of YJR092W:''' Anillin-like protein involved in bud-site selection; required for the axial budding pattern; localizes with septins to the bud neck in mitosis and may constitute an axial landmark for the next round of budding; required for the formation and disassembly of the double septin ring structure, and generally for septin organization; in vivo substrate of Cdc28p/Clb2p<ref name='S000042162'>Chant J and Herskowitz I (1991) Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway. Cell 65(7):1203-12 {{SGDpaper|S000042162}} PMID 2065354</ref><ref name='S000147866'>Eluere R, et al. (2012) Cdk and the anillin homolog Bud4 define a new pathway regulating septin organization in yeast. Cell Cycle 11(1) {{SGDpaper|S000147866}} PMID 22185758</ref><ref name='S000046978'>Sanders SL and Herskowitz I (1996) The BUD4 protein of yeast, required for axial budding, is localized to the mother/BUD neck in a cell cycle-dependent manner. J Cell Biol 134(2):413-27 {{SGDpaper|S000046978}} PMID 8707826</ref><ref name='S000146330'>Wloka C, et al. (2011) Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast. Biol Chem 392(8-9):813-829 |
{{SGDpaper|S000146330}} PMID 21824009</ref> | {{SGDpaper|S000146330}} PMID 21824009</ref> | ||
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Revision as of 13:05, 20 January 2012
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| Systematic name | YJR092W |
| Gene name | BUD4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:598735..603078 |
| Primary SGDID | S000003852 |
Description of YJR092W: Anillin-like protein involved in bud-site selection; required for the axial budding pattern; localizes with septins to the bud neck in mitosis and may constitute an axial landmark for the next round of budding; required for the formation and disassembly of the double septin ring structure, and generally for septin organization; in vivo substrate of Cdc28p/Clb2p[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Chant J and Herskowitz I (1991) Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway. Cell 65(7):1203-12 SGD PMID 2065354
- ↑ Eluere R, et al. (2012) Cdk and the anillin homolog Bud4 define a new pathway regulating septin organization in yeast. Cell Cycle 11(1) SGD PMID 22185758
- ↑ Sanders SL and Herskowitz I (1996) The BUD4 protein of yeast, required for axial budding, is localized to the mother/BUD neck in a cell cycle-dependent manner. J Cell Biol 134(2):413-27 SGD PMID 8707826
- ↑ Wloka C, et al. (2011) Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast. Biol Chem 392(8-9):813-829 SGD PMID 21824009
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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