YJR092W

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Systematic name YJR092W
Gene name BUD4
Aliases
Feature type ORF, Verified
Coordinates Chr X:598735..603078
Primary SGDID S000003852


Description of YJR092W: Anillin-like protein involved in bud-site selection; required for the axial budding pattern; localizes with septins to the bud neck in mitosis and may constitute an axial landmark for the next round of budding; required for the formation and disassembly of the double septin ring structure, and generally for septin organization; in vivo substrate of Cdc28p/Clb2p[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Chant J and Herskowitz I (1991) Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway. Cell 65(7):1203-12 SGD PMID 2065354
  2. Eluere R, et al. (2012) Cdk and the anillin homolog Bud4 define a new pathway regulating septin organization in yeast. Cell Cycle 11(1) SGD PMID 22185758
  3. Sanders SL and Herskowitz I (1996) The BUD4 protein of yeast, required for axial budding, is localized to the mother/BUD neck in a cell cycle-dependent manner. J Cell Biol 134(2):413-27 SGD PMID 8707826
  4. Wloka C, et al. (2011) Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast. Biol Chem 392(8-9):813-829 SGD PMID 21824009
  5. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. submitted by Jeff Ubersax on 2004-01-27

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