Difference between revisions of "tE(UUC)G1"
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| − | '''Description of tE(UUC)G1:''' Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p; target of K. lactis zymocin<ref name='S000123162'>Bjork GR, et al. (2007) A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA 13(8):1245-55 {{SGDpaper|S000123162}} PMID 17592039</ref><ref name='S000147623'>Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 {{SGDpaper|S000147623}} PMID 18984615</ref><ref name='S000127524'>Huang B, et al. (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 | + | '''Description of tE(UUC)G1:''' Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p; can mutate to become a missense suppressor tRNA that inserts glutamate residues at lysine codons; target of K. lactis zymocin<ref name='S000123162'>Bjork GR, et al. (2007) A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA 13(8):1245-55 {{SGDpaper|S000123162}} PMID 17592039</ref><ref name='S000147623'>Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 {{SGDpaper|S000147623}} PMID 18984615</ref><ref name='S000127524'>Huang B, et al. (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 {{SGDpaper|S000127524}} PMID 18755837</ref><ref name='S000047275'>Su JY, et al. (1990) Genetic and molecular analysis of the SOE1 gene: a tRNA(3Glu) missense suppressor of yeast cdc8 mutations. Genetics 124(3):523-31 |
| − | {{SGDpaper| | + | {{SGDpaper|S000047275}} PMID 2155851</ref> |
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Revision as of 13:05, 9 December 2011
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| Systematic name | tE(UUC)G1 |
| Gene name | SOE1 |
| Aliases | |
| Feature type | tRNA |
| Coordinates | Chr VII:328583..328654 |
| Primary SGDID | S000006553 |
Description of tE(UUC)G1: Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p; can mutate to become a missense suppressor tRNA that inserts glutamate residues at lysine codons; target of K. lactis zymocin[1][2][3][4]
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References
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- ↑ Bjork GR, et al. (2007) A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA 13(8):1245-55 SGD PMID 17592039
- ↑ Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 SGD PMID 18984615
- ↑ Huang B, et al. (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD PMID 18755837
- ↑ Su JY, et al. (1990) Genetic and molecular analysis of the SOE1 gene: a tRNA(3Glu) missense suppressor of yeast cdc8 mutations. Genetics 124(3):523-31 SGD PMID 2155851
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