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Systematic name tE(UUC)G1
Gene name SOE1
Feature type tRNA
Coordinates Chr VII:328583..328654
Primary SGDID S000006553

Description of tE(UUC)G1: Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p; can mutate to become a missense suppressor tRNA that inserts glutamate residues at lysine codons; target of K. lactis zymocin[1][2][3][4]


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  1. Bjork GR, et al. (2007) A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA 13(8):1245-55 SGD PMID 17592039
  2. Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 SGD PMID 18984615
  3. Huang B, et al. (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD PMID 18755837
  4. Su JY, et al. (1990) Genetic and molecular analysis of the SOE1 gene: a tRNA(3Glu) missense suppressor of yeast cdc8 mutations. Genetics 124(3):523-31 SGD PMID 2155851

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