Difference between revisions of "tK(UUU)Q"

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'''Description of tK(UUU)Q:''' Mitochondrial tRNA-Lys; modification of wobble base U34 is decreased at elevated temperatures, decreasing ability to decode AAG codons; this function is performed at high temperature by imported cytoplasmic tRNA-Lys with CUU anticodon<ref name='S000058438'>Foury F, et al. (1998) The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae. FEBS Lett 440(3):325-31 {{SGDpaper|S000058438}} PMID 9872396</ref><ref name='S000122987'>Kamenski P, et al. (2007) Evidence for an Adaptation Mechanism of Mitochondrial Translation via tRNA Import from the Cytosol. Mol Cell 26(5):625-37
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'''Description of tK(UUU)Q:''' Mitochondrial lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; modification of wobble base U34 is decreased at elevated temperatures, decreasing ability to decode AAG codons; this function is performed at high temperature by imported cytoplasmic tRNA-Lys with CUU anticodon<ref name='S000147623'>Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 {{SGDpaper|S000147623}} PMID 18984615</ref><ref name='S000058438'>Foury F, et al. (1998) The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae. FEBS Lett 440(3):325-31 {{SGDpaper|S000058438}} PMID 9872396</ref><ref name='S000122987'>Kamenski P, et al. (2007) Evidence for an Adaptation Mechanism of Mitochondrial Translation via tRNA Import from the Cytosol. Mol Cell 26(5):625-37
 
  {{SGDpaper|S000122987}} PMID 17560369</ref>
 
  {{SGDpaper|S000122987}} PMID 17560369</ref>
 
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Revision as of 13:05, 6 December 2011

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Systematic name tK(UUU)Q
Gene name
Aliases
Feature type tRNA
Coordinates Mito:67061..67134
Primary SGDID S000007323


Description of tK(UUU)Q: Mitochondrial lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; modification of wobble base U34 is decreased at elevated temperatures, decreasing ability to decode AAG codons; this function is performed at high temperature by imported cytoplasmic tRNA-Lys with CUU anticodon[1][2][3]




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References

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  1. Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 SGD PMID 18984615
  2. Foury F, et al. (1998) The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae. FEBS Lett 440(3):325-31 SGD PMID 9872396
  3. Kamenski P, et al. (2007) Evidence for an Adaptation Mechanism of Mitochondrial Translation via tRNA Import from the Cytosol. Mol Cell 26(5):625-37 SGD PMID 17560369

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