Difference between revisions of "YKR082W"
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| − | '''Description of YKR082W:''' Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) | + | '''Description of YKR082W:''' Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; required also for transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay<ref name='S000074016'>Allen NP, et al. (2002) Deciphering networks of protein interactions at the nuclear pore complex. Mol Cell Proteomics 1(12):930-46 {{SGDpaper|S000074016}} PMID 12543930</ref><ref name='S000068846'>Gao H, et al. (2003) Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p. J Biol Chem 278(28):25331-40 {{SGDpaper|S000068846}} PMID 12730220</ref><ref name='S000056415'>Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 {{SGDpaper|S000056415}} PMID 10684247</ref><ref name='S000146226'>Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 |
| − | {{SGDpaper| | + | {{SGDpaper|S000146226}} PMID 21478823</ref> |
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Revision as of 13:05, 15 August 2011
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| Systematic name | YKR082W |
| Gene name | NUP133 |
| Aliases | RAT3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:592825..596298 |
| Primary SGDID | S000001790 |
Description of YKR082W: Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; required also for transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay[1][2][3][4]
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References
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- ↑ Allen NP, et al. (2002) Deciphering networks of protein interactions at the nuclear pore complex. Mol Cell Proteomics 1(12):930-46 SGD PMID 12543930
- ↑ Gao H, et al. (2003) Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p. J Biol Chem 278(28):25331-40 SGD PMID 12730220
- ↑ Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
- ↑ Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 SGD PMID 21478823
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