Difference between revisions of "YMR038C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:348259..347510
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|nowrap| Chr XIII:348260..347511
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004641
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004641

Revision as of 13:05, 3 February 2011

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Systematic name YMR038C
Gene name CCS1
Aliases CCS, LYS7
Feature type ORF, Verified
Coordinates Chr XIII:348260..347511
Primary SGDID S000004641


Description of YMR038C: Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation[1][2]




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References

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  1. Brown NM, et al. (2004) Oxygen and the copper chaperone CCS regulate posttranslational activation of Cu,Zn superoxide dismutase. Proc Natl Acad Sci U S A 101(15):5518-23 SGD PMID 15064408
  2. Schmidt PJ, et al. (1999) A gain of superoxide dismutase (SOD) activity obtained with CCS, the copper metallochaperone for SOD1. J Biol Chem 274(52):36952-6 SGD PMID 10601249

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