YMR038C

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Systematic name YMR038C
Gene name CCS1
Aliases CCS, LYS7
Feature type ORF, Verified
Coordinates Chr XIII:348260..347511
Primary SGDID S000004641


Description of YMR038C: Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation[1][2]




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References

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  1. Brown NM, et al. (2004) Oxygen and the copper chaperone CCS regulate posttranslational activation of Cu,Zn superoxide dismutase. Proc Natl Acad Sci U S A 101(15):5518-23 SGD PMID 15064408
  2. Schmidt PJ, et al. (1999) A gain of superoxide dismutase (SOD) activity obtained with CCS, the copper metallochaperone for SOD1. J Biol Chem 274(52):36952-6 SGD PMID 10601249

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