Difference between revisions of "YHR191C"

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=== Alleles, Strains, and Phenotypes ===
 
[[Category:Topic:Alleles, Strains, and Phenotypes]]
 
==== Complete Deletion ====
 
[[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]]
 
'''Phenotype(s)''': Viable [[Category:Phenotype:Viable]]
 
 
Deletion mutant is defective in telomere positioning to nuclear periphery. <ref name='S000114577'>Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 {{SGDpaper|S000114577}} PMID 16525505</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref>
 
 
{{ShortCenteredHR}}
 
==== Multiple Knockout Strains ====
 
[[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]]
 
'''Together with''': DCC1, RAD9<br>
 
'''Phenotype(s)''': Viable [[Category:Phenotype:Viable]]
 
 
ctf8 rad9 double deletion strain is defective in phosphorulation of Rad53p in responce to HU and MMS. <ref name='S000114451'>Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 {{SGDpaper|S000114451}} PMID 16487579</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref>
 
 
{{ShortCenteredHR}}
 
 
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==Community Commentary==
 
==Community Commentary==

Revision as of 10:51, 24 January 2007

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Systematic name YHR191C
Gene name CTF8
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:486631..486230
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Description of YHR191C: Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion[1]



Community Commentary

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Alleles, Strains, and Phenotypes

Complete Deletion

Phenotype(s): Viable

Deletion mutant is defective in telomere positioning to nuclear periphery. [2] [3]


Multiple Knockout Strains

Together with: DCC1, RAD9
Phenotype(s): Viable

ctf8 rad9 double deletion strain is defective in phosphorulation of Rad53p in responce to HU and MMS. [4] [3]


References

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  1. Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
  2. Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
  3. 3.0 3.1 submitted by Shin-ichiro Hiraga on 2006-06-20
  4. Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 SGD PMID 16487579

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