YHR191C
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| Systematic name | YHR191C |
| Gene name | CTF8 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:486631..486230 |
| Primary SGDID | S000001234 |
Description of YHR191C: Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion[1]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Viable
Deletion mutant is defective in telomere positioning to nuclear periphery. [2] [3]
Multiple Knockout Strains
Together with: DCC1, RAD9
Phenotype(s): Viable
ctf8 rad9 double deletion strain is defective in phosphorulation of Rad53p in responce to HU and MMS. [4] [3]
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References
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- ↑ Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
- ↑ Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
- ↑ 3.0 3.1 submitted by Shin-ichiro Hiraga on 2006-06-20
- ↑ Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 SGD PMID 16487579
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