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| − | === Alleles, Strains, and Phenotypes ===
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| − | [[Category:Topic:Alleles, Strains, and Phenotypes]]
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| − | ==== Multiple Knockout Strains ====
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| − | [[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]]
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| − |
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| − | '''Strain Background''': Sigma1278b (Sigma2000 series)<br>
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| − | '''Genotype''': MCY4581<br>
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| − | '''Together with''': NRG2, NRG1, GAL83, SIP2<br>
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| − | '''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
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| − |
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| − | Deletion of SIP1 suppresses gal83's defect in invasive growth in response to glucose limitation. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
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| − |
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| − | {{ShortCenteredHR}}
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| − |
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| − | '''Strain Background''': Sigma1278b (Sigma2000 series)<br>
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| − | '''Genotype''': MCY4600<br>
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| − | '''Together with''': REG1, GAL83, SIP2, MUC1<br>
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| − | '''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
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| − |
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| − | Deletion of SIP1 in a gal83 sip2 double mutant causes an increase in invasion, suggesting Sip1 negatively regulates invasive growth. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
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| − |
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| − | {{ShortCenteredHR}}
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| − |
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| − | '''Strain Background''': Sigma1278b (Sigma2000 series)<br>
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| − | '''Genotype''': MCY4600<br>
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| − | '''Together with''': REG1, GAL83, SIP2, MUC1<br>
| |
| − | '''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
| |
| − |
| |
| − | Deletion of SIP1 in a gal83 sip2 double mutant causes an increase in invasion, suggesting Sip1 negatively regulates invasive growth. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
| |
| − |
| |
| − | {{ShortCenteredHR}}
| |
| − |
| |
| − | '''Strain Background''': Sigma1278b (Sigma2000 series)<br>
| |
| − | '''Genotype''': MCY4581<br>
| |
| − | '''Together with''': NRG2, NRG1, GAL83, SIP2<br>
| |
| − | '''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
| |
| − |
| |
| − | Deletion of SIP1 suppresses gal83's defect in invasive growth in response to glucose limitation. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
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| − |
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| − | {{ShortCenteredHR}}
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| − | === Protein Details ===
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| − | [[Category:Topic:Protein Details]]
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| − | ==== Protein Function/Process ====
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| − | [[Category:Topic:Protein Details:Protein Function/Process]]
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| − |
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| − | One of three alternative beta subunits of the Snf1 kinase complex <ref name='S000059161'>Schmidt MC and McCartney RR (2000) beta-subunits of Snf1 kinase are required for kinase function and substrate definition. EMBO J 19(18):4936-43 {{SGDpaper|S000059161}} PMID 10990457</ref> <ref name = 'CAset5180-2003-02-17'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5180 Martin C. Schmidt] on 2003-02-17</ref>
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| − | {{ShortCenteredHR}}
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| | __TOC__ | | __TOC__ |
| | ==Community Commentary== | | ==Community Commentary== |
Share your knowledge...Edit this entry!
| Systematic name |
YDR422C
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| Gene name |
SIP1
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| Aliases |
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| Feature type |
ORF, Verified
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| Coordinates
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Chr IV:1317765..1315318
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| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs.
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Description of YDR422C: Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions[1][2][3]
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4581
Together with: NRG2, NRG1, GAL83, SIP2
Phenotype(s): Loss of function (Null)
Deletion of SIP1 suppresses gal83's defect in invasive growth in response to glucose limitation. [4] [5]
Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4600
Together with: REG1, GAL83, SIP2, MUC1
Phenotype(s): Loss of function (Null)
Deletion of SIP1 in a gal83 sip2 double mutant causes an increase in invasion, suggesting Sip1 negatively regulates invasive growth. [4] [5]
Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4600
Together with: REG1, GAL83, SIP2, MUC1
Phenotype(s): Loss of function (Null)
Deletion of SIP1 in a gal83 sip2 double mutant causes an increase in invasion, suggesting Sip1 negatively regulates invasive growth. [4] [5]
Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4581
Together with: NRG2, NRG1, GAL83, SIP2
Phenotype(s): Loss of function (Null)
Deletion of SIP1 suppresses gal83's defect in invasive growth in response to glucose limitation. [4] [5]
Protein Details
Protein Function/Process
One of three alternative beta subunits of the Snf1 kinase complex [3] [6]
References
See Help:References on how to add references
- ↑ Schuller HJ (2003) Transcriptional control of nonfermentative metabolism in the yeast Saccharomyces cerevisiae. Curr Genet 43(3):139-60 SGD PMID 12715202
- ↑ Vincent O, et al. (2001) Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism. Genes Dev 15(9):1104-14 SGD PMID 11331606
- ↑ 3.0 3.1 Schmidt MC and McCartney RR (2000) beta-subunits of Snf1 kinase are required for kinase function and substrate definition. EMBO J 19(18):4936-43
SGD PMID 10990457 Cite error: Invalid
<ref> tag; name "S000059161" defined multiple times with different content
- ↑ 4.0 4.1 4.2 4.3 Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 SGD PMID 12556493
- ↑ 5.0 5.1 5.2 5.3 submitted by Valmik K. Vyas on 2003-03-27
- ↑ submitted by Martin C. Schmidt on 2003-02-17
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