Difference between revisions of "YPL175W"
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| − | '''Description of YPL175W:''' UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins | + | '''Description of YPL175W:''' UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins<ref name='S000063370'>Kostova Z, et al. (2000) Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis. Biochem J 350 Pt 3():815-22 {{SGDpaper|S000063370}} PMID 10970797</ref><ref name='S000043664'>Vossen JH, et al. (1995) Identification of SPT14/CWH6 as the yeast homologue of hPIG-A, a gene involved in the biosynthesis of GPI anchors. Biochim Biophys Acta 1243(3):549-51 |
| − | {{SGDpaper| | + | {{SGDpaper|S000043664}} PMID 7727533</ref> |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YPL175W |
| Gene name | SPT14 |
| Aliases | CWH6, GPI3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:218629..220087 |
| Primary SGDID | S000006096 |
Description of YPL175W: UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins[1][2]
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References
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- ↑ Kostova Z, et al. (2000) Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis. Biochem J 350 Pt 3():815-22 SGD PMID 10970797
- ↑ Vossen JH, et al. (1995) Identification of SPT14/CWH6 as the yeast homologue of hPIG-A, a gene involved in the biosynthesis of GPI anchors. Biochim Biophys Acta 1243(3):549-51 SGD PMID 7727533
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