Difference between revisions of "YML097C"
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| − | '''Description of YML097C:''' A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin | + | '''Description of YML097C:''' A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin<ref name='S000046859'>Burd CG, et al. (1996) A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins. Mol Cell Biol 16(5):2369-77 {{SGDpaper|S000046859}} PMID 8628304</ref><ref name='S000073618'>Davies BA, et al. (2003) Vps9p CUE domain ubiquitin binding is required for efficient endocytic protein traffic. J Biol Chem 278(22):19826-33 {{SGDpaper|S000073618}} PMID 12654912</ref><ref name='S000046430'>Hama H, et al. (1999) Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport. J Biol Chem 274(21):15284-91 |
| − | {{SGDpaper| | + | {{SGDpaper|S000046430}} PMID 10329739</ref> |
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Revision as of 14:05, 25 February 2010
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| Systematic name | YML097C |
| Gene name | VPS9 |
| Aliases | VPL31, VPT9 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:79690..78335 |
| Primary SGDID | S000004563 |
Description of YML097C: A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin[1][2][3]
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References
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- ↑ Burd CG, et al. (1996) A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins. Mol Cell Biol 16(5):2369-77 SGD PMID 8628304
- ↑ Davies BA, et al. (2003) Vps9p CUE domain ubiquitin binding is required for efficient endocytic protein traffic. J Biol Chem 278(22):19826-33 SGD PMID 12654912
- ↑ Hama H, et al. (1999) Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport. J Biol Chem 274(21):15284-91 SGD PMID 10329739
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