YML097C

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Systematic name YML097C
Gene name VPS9
Aliases VPL31, VPT9
Feature type ORF, Verified
Coordinates Chr XIII:79690..78335
Primary SGDID S000004563


Description of YML097C: A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin[1][2][3]




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References

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  1. Burd CG, et al. (1996) A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins. Mol Cell Biol 16(5):2369-77 SGD PMID 8628304
  2. Davies BA, et al. (2003) Vps9p CUE domain ubiquitin binding is required for efficient endocytic protein traffic. J Biol Chem 278(22):19826-33 SGD PMID 12654912
  3. Hama H, et al. (1999) Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport. J Biol Chem 274(21):15284-91 SGD PMID 10329739

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