Difference between revisions of "YHR165C"
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with Prp40 [[Category:Two Hybrid Interactions with Prp40]]<br> | ||
| + | Prp8 interacts with the U1snRNP protein Prp40 <ref name='S000040368'>Abovich N and Rosbash M (1997) Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89(3):403-12 {{SGDpaper|S000040368}} PMID 9150140</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Snp1 [[Category:Two Hybrid Interactions with Snp1]]<br> | ||
| + | Prp8 interacts with the U1snRNP protein Snp1 <ref name='S000069169'>Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 {{SGDpaper|S000069169}} PMID 11425851</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Exo84 [[Category:Two Hybrid Interactions with Exo84]]<br> | ||
| + | Prp8 binds to C-terminus of Exo84 <ref name='S000052181'>Kuhn AN and Brow DA (2000) Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155(4):1667-82 {{SGDpaper|S000052181}} PMID 10924465</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Prp39 [[Category:Two Hybrid Interactions with Prp39]]<br> | ||
| + | N-terminal region of Prp8 interacts with Prp39 <ref name='S000060204'>van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 {{SGDpaper|S000060204}} PMID 11290703</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Brr2 [[Category:Two Hybrid Interactions with Brr2]]<br> | ||
| + | C-terminus of Prp8 binds to full length Brr2. N-terminus of Prp8 binds to Prp39 <ref name='S000060204'>van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 {{SGDpaper|S000060204}} PMID 11290703</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with Prp40 [[Category:Two Hybrid Interactions with Prp40]]<br> | ||
| + | Prp8 interacts with the U1snRNP protein Prp40 <ref name='S000040368'>Abovich N and Rosbash M (1997) Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89(3):403-12 {{SGDpaper|S000040368}} PMID 9150140</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Snp1 [[Category:Two Hybrid Interactions with Snp1]]<br> | ||
| + | Prp8 interacts with the U1snRNP protein Snp1 <ref name='S000069169'>Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 {{SGDpaper|S000069169}} PMID 11425851</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Exo84 [[Category:Two Hybrid Interactions with Exo84]]<br> | ||
| + | Prp8 binds to C-terminus of Exo84 <ref name='S000052181'>Kuhn AN and Brow DA (2000) Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155(4):1667-82 {{SGDpaper|S000052181}} PMID 10924465</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Prp39 [[Category:Two Hybrid Interactions with Prp39]]<br> | ||
| + | N-terminal region of Prp8 interacts with Prp39 <ref name='S000060204'>van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 {{SGDpaper|S000060204}} PMID 11290703</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Brr2 [[Category:Two Hybrid Interactions with Brr2]]<br> | ||
| + | C-terminus of Prp8 binds to full length Brr2. N-terminus of Prp8 binds to Prp39 <ref name='S000060204'>van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 {{SGDpaper|S000060204}} PMID 11290703</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
Revision as of 16:05, 23 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YHR165C | |
| Gene name | PRP8 | |
| Aliases | DBF3, DNA39, RNA8, SLT21, USA2 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr VIII:436950..429709 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YHR165C: Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing[1][2]
Interactions
Two Hybrid
Two Hybrid interaction with Prp40
Prp8 interacts with the U1snRNP protein Prp40 [3] [4]
Two Hybrid interaction with Snp1
Prp8 interacts with the U1snRNP protein Snp1 [5] [4]
Two Hybrid interaction with Exo84
Prp8 binds to C-terminus of Exo84 [6] [4]
Two Hybrid interaction with Prp39
N-terminal region of Prp8 interacts with Prp39 [7] [4]
Two Hybrid interaction with Brr2
C-terminus of Prp8 binds to full length Brr2. N-terminus of Prp8 binds to Prp39 [7] [4]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Two Hybrid
Two Hybrid interaction with Prp40
Prp8 interacts with the U1snRNP protein Prp40 [3] [4]
Two Hybrid interaction with Snp1
Prp8 interacts with the U1snRNP protein Snp1 [5] [4]
Two Hybrid interaction with Exo84
Prp8 binds to C-terminus of Exo84 [6] [4]
Two Hybrid interaction with Prp39
N-terminal region of Prp8 interacts with Prp39 [7] [4]
Two Hybrid interaction with Brr2
C-terminus of Prp8 binds to full length Brr2. N-terminus of Prp8 binds to Prp39 [7] [4]
References
See Help:References on how to add references
- ↑ Umen JG and Guthrie C (1995) The second catalytic step of pre-mRNA splicing. RNA 1(9):869-85 SGD PMID 8548652
- ↑ Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31 SGD PMID 10377396
- ↑ 3.0 3.1 Abovich N and Rosbash M (1997) Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89(3):403-12 SGD PMID 9150140
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 submitted by Richard Grainger on 2003-04-11
- ↑ 5.0 5.1 Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 SGD PMID 11425851
- ↑ 6.0 6.1 Kuhn AN and Brow DA (2000) Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155(4):1667-82 SGD PMID 10924465
- ↑ 7.0 7.1 7.2 7.3 van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 SGD PMID 11290703
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