Difference between revisions of "YHL022C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
Line 23: | Line 23: | ||
<br> | <br> | ||
<br> | <br> | ||
+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Two Hybrid ==== | ||
+ | [[Category:Topic:Interactions:Two Hybrid]] | ||
+ | Two Hybrid interaction with Rec104 [[Category:Two Hybrid Interactions with Rec104]]<br> | ||
+ | meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
+ | {{ShortCenteredHR}} | ||
+ | Two Hybrid interaction with ski8 [[Category:Two Hybrid Interactions with ski8]]<br> <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | === Protein Details === | ||
+ | [[Category:Topic:Protein Details]] | ||
+ | ==== Protein Modification ==== | ||
+ | [[Category:Topic:Protein Details:Protein Modification]] | ||
+ | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
+ | |||
+ | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-27</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Two Hybrid ==== | ||
+ | [[Category:Topic:Interactions:Two Hybrid]] | ||
+ | Two Hybrid interaction with Rec104 [[Category:Two Hybrid Interactions with Rec104]]<br> | ||
+ | meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Two Hybrid interaction with ski8 [[Category:Two Hybrid Interactions with ski8]]<br> <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | === Protein Details === | ||
+ | [[Category:Topic:Protein Details]] | ||
+ | ==== Protein Modification ==== | ||
+ | [[Category:Topic:Protein Details:Protein Modification]] | ||
+ | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
+ | |||
+ | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-27</ref> | ||
+ | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} |
Revision as of 17:05, 23 January 2007
Share your knowledge...Edit this entry!
Systematic name | YHL022C | |
Gene name | SPO11 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr VIII:64155..62959 | |
Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. |
Description of YHL022C: Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation[1][2]
Interactions
Two Hybrid
Two Hybrid interaction with Rec104
meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes [3] [4]
Two Hybrid interaction with ski8
[3] [4]
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Two Hybrid
Two Hybrid interaction with Rec104
meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes [3] [4]
Two Hybrid interaction with ski8
[3] [4]
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
References
See Help:References on how to add references
- ↑ Lichten M (2001) Meiotic recombination: breaking the genome to save it. Curr Biol 11(7):R253-6 SGD PMID 11413012
- ↑ Keeney S, et al. (1997) Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family. Cell 88(3):375-84 SGD PMID 9039264
- ↑ 3.0 3.1 3.2 3.3 Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 SGD PMID 14992724
- ↑ 4.0 4.1 4.2 4.3 submitted by Scott Keeney on 2004-05-02
- ↑ 5.0 5.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ 6.0 6.1 submitted by Jeff Ubersax on 2004-01-27
See Help:Categories on how to add the wiki page for this gene to a Category