Difference between revisions of "YCL016C"
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+ | === Alleles, Strains, and Phenotypes === | ||
+ | [[Category:Topic:Alleles, Strains, and Phenotypes]] | ||
+ | ==== Complete Deletion ==== | ||
+ | [[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]] | ||
+ | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
+ | Deletion mutant is defective in telomere positioning to nuclear periphery. <ref name='S000114577'>Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 {{SGDpaper|S000114577}} PMID 16525505</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | ==== Multiple Knockout Strains ==== | ||
+ | [[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]] | ||
+ | '''Together with''': RAD9, CTF8<br> | ||
+ | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
+ | |||
+ | dcc1 rad9 double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. <ref name='S000114451'>Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 {{SGDpaper|S000114451}} PMID 16487579</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
+ | === Alleles, Strains, and Phenotypes === | ||
+ | [[Category:Topic:Alleles, Strains, and Phenotypes]] | ||
+ | ==== Complete Deletion ==== | ||
+ | [[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]] | ||
+ | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
+ | |||
+ | Deletion mutant is defective in telomere positioning to nuclear periphery. <ref name='S000114577'>Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 {{SGDpaper|S000114577}} PMID 16525505</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | ==== Multiple Knockout Strains ==== | ||
+ | [[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]] | ||
+ | '''Together with''': RAD9, CTF8<br> | ||
+ | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
+ | |||
+ | dcc1 rad9 double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. <ref name='S000114451'>Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 {{SGDpaper|S000114451}} PMID 16487579</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
+ | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} |
Revision as of 17:05, 23 January 2007
Share your knowledge...Edit this entry!
Systematic name | YCL016C | |
Gene name | DCC1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr III:95763..94621 | |
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Description of YCL016C: Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance[1][2]
Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Viable
Deletion mutant is defective in telomere positioning to nuclear periphery. [3] [4]
Multiple Knockout Strains
Together with: RAD9, CTF8
Phenotype(s): Viable
dcc1 rad9 double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. [5] [4]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Viable
Deletion mutant is defective in telomere positioning to nuclear periphery. [3] [4]
Multiple Knockout Strains
Together with: RAD9, CTF8
Phenotype(s): Viable
dcc1 rad9 double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. [5] [4]
References
See Help:References on how to add references
- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
- ↑ 3.0 3.1 Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
- ↑ 4.0 4.1 4.2 4.3 submitted by Shin-ichiro Hiraga on 2006-06-20
- ↑ 5.0 5.1 Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 SGD PMID 16487579
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