Difference between revisions of "YDR069C"

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'''Description of YDR069C:''' Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole<ref name='S000059113'>Amerik AY, et al. (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80 {{SGDpaper|S000059113}} PMID 11029042</ref><ref name='S000054052'>Singer JD, et al. (1996) Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism. Mol Cell Biol 16(4):1356-66 {{SGDpaper|S000054052}} PMID 8657109</ref><ref name='S000046087'>Swaminathan S, et al. (1999) The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast. Mol Biol Cell 10(8):2583-94
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'''Description of YDR069C:''' Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole<ref name='S000046087'>Swaminathan S, et al. (1999) The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast. Mol Biol Cell 10(8):2583-94 {{SGDpaper|S000046087}} PMID 10436014</ref><ref name='S000054052'>Singer JD, et al. (1996) Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism. Mol Cell Biol 16(4):1356-66 {{SGDpaper|S000054052}} PMID 8657109</ref><ref name='S000059113'>Amerik AY, et al. (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80
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  {{SGDpaper|S000059113}} PMID 11029042</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YDR069C
Gene name DOA4
Aliases DOS1, MUT4, NPI2, SSV7, UBP4
Feature type ORF, Verified
Coordinates Chr IV:587718..584938
Primary SGDID S000002476


Description of YDR069C: Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole[1][2][3]




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References

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  1. Swaminathan S, et al. (1999) The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast. Mol Biol Cell 10(8):2583-94 SGD PMID 10436014
  2. Singer JD, et al. (1996) Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism. Mol Cell Biol 16(4):1356-66 SGD PMID 8657109
  3. Amerik AY, et al. (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80 SGD PMID 11029042

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