Difference between revisions of "YBR156C"

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'''Description of YBR156C:''' Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase<ref name='S000041165'>Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94 {{SGDpaper|S000041165}} PMID 10385519</ref><ref name='S000068910'>Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 {{SGDpaper|S000068910}} PMID 11731476</ref><ref name='S000069415'>Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29 {{SGDpaper|S000069415}} PMID 11853667</ref><ref name='S000078515'>Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 {{SGDpaper|S000078515}} PMID 12566427</ref><ref name='S000080225'>D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95
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'''Description of YBR156C:''' Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase<ref name='S000080225'>D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95 {{SGDpaper|S000080225}} PMID 15520278</ref><ref name='S000078515'>Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 {{SGDpaper|S000078515}} PMID 12566427</ref><ref name='S000069415'>Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29 {{SGDpaper|S000069415}} PMID 11853667</ref><ref name='S000068910'>Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 {{SGDpaper|S000068910}} PMID 11731476</ref><ref name='S000041165'>Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94
  {{SGDpaper|S000080225}} PMID 15520278</ref>
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  {{SGDpaper|S000041165}} PMID 10385519</ref>
 
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Revision as of 13:05, 16 January 2009

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Systematic name YBR156C
Gene name SLI15
Aliases
Feature type ORF, Verified
Coordinates Chr II:553194..551098
Primary SGDID S000000360


Description of YBR156C: Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase[1][2][3][4][5]




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References

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  1. D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95 SGD PMID 15520278
  2. Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 SGD PMID 12566427
  3. Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29 SGD PMID 11853667
  4. Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 SGD PMID 11731476
  5. Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94 SGD PMID 10385519

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