Difference between revisions of "YBL079W"
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| − | '''Description of YBL079W:''' Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation, has similarity to Nup157p<ref name=' | + | '''Description of YBL079W:''' Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation, has similarity to Nup157p<ref name='S000060228'>Kerscher O, et al. (2001) Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics 157(4):1543-53 {{SGDpaper|S000060228}} PMID 11290711</ref><ref name='S000057786'>Aitchison JD, et al. (1995) Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p. J Cell Biol 131(5):1133-48 {{SGDpaper|S000057786}} PMID 8522578</ref><ref name='S000056415'>Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 {{SGDpaper|S000056415}} PMID 10684247</ref><ref name='S000046344'>Kenna MA, et al. (1996) Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. Mol Cell Biol 16(5):2025-36 {{SGDpaper|S000046344}} PMID 8628268</ref><ref name='S000045804'>Shulga N, et al. (2000) Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol 149(5):1027-38 |
| − | {{SGDpaper| | + | {{SGDpaper|S000045804}} PMID 10831607</ref> |
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Revision as of 13:05, 16 January 2009
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| Systematic name | YBL079W |
| Gene name | NUP170 |
| Aliases | NLE3 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:75256..79764 |
| Primary SGDID | S000000175 |
Description of YBL079W: Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation, has similarity to Nup157p[1][2][3][4][5]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Loss of function (Null)
Null mutants display defects in chromosome transmission fidelity and kinetochore integrity [1] [6]
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References
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- ↑ 1.0 1.1 Kerscher O, et al. (2001) Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics 157(4):1543-53 SGD PMID 11290711
- ↑ Aitchison JD, et al. (1995) Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p. J Cell Biol 131(5):1133-48 SGD PMID 8522578
- ↑ Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
- ↑ Kenna MA, et al. (1996) Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. Mol Cell Biol 16(5):2025-36 SGD PMID 8628268
- ↑ Shulga N, et al. (2000) Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol 149(5):1027-38 SGD PMID 10831607
- ↑ submitted by Munira Basrai on 2005-07-29
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