Difference between revisions of "YDL227C"

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'''Description of YDL227C:''' Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p<ref name='S000053754'>Kostriken R, et al. (1983) A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell 35(1):167-74 {{SGDpaper|S000053754}} PMID 6313222</ref><ref name='S000049724'>Strathern JN, et al. (1982) Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus. Cell 31(1):183-92 {{SGDpaper|S000049724}} PMID 6297747</ref><ref name='S000046898'>Jensen R, et al. (1983) Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus. Proc Natl Acad Sci U S A 80(10):3035-9 {{SGDpaper|S000046898}} PMID 6344075</ref><ref name='S000044798'>Nasmyth K (1993) Regulating the HO endonuclease in yeast. Curr Opin Genet Dev 3(2):286-94
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'''Description of YDL227C:''' Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p<ref name='S000044798'>Nasmyth K (1993) Regulating the HO endonuclease in yeast. Curr Opin Genet Dev 3(2):286-94 {{SGDpaper|S000044798}} PMID 8504254</ref><ref name='S000046898'>Jensen R, et al. (1983) Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus. Proc Natl Acad Sci U S A 80(10):3035-9 {{SGDpaper|S000046898}} PMID 6344075</ref><ref name='S000049724'>Strathern JN, et al. (1982) Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus. Cell 31(1):183-92 {{SGDpaper|S000049724}} PMID 6297747</ref><ref name='S000053754'>Kostriken R, et al. (1983) A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell 35(1):167-74
  {{SGDpaper|S000044798}} PMID 8504254</ref>
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  {{SGDpaper|S000053754}} PMID 6313222</ref>
 
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Revision as of 03:15, 19 December 2008

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Systematic name YDL227C
Gene name HO
Aliases
Feature type ORF, Verified
Coordinates Chr IV:48032..46272
Primary SGDID S000002386


Description of YDL227C: Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p[1][2][3][4]




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References

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  1. Nasmyth K (1993) Regulating the HO endonuclease in yeast. Curr Opin Genet Dev 3(2):286-94 SGD PMID 8504254
  2. Jensen R, et al. (1983) Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus. Proc Natl Acad Sci U S A 80(10):3035-9 SGD PMID 6344075
  3. Strathern JN, et al. (1982) Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus. Cell 31(1):183-92 SGD PMID 6297747
  4. Kostriken R, et al. (1983) A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell 35(1):167-74 SGD PMID 6313222

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