YDL227C
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| Systematic name | YDL227C |
| Gene name | HO |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:48031..46271 |
| Primary SGDID | S000002386 |
Description of YDL227C: Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p[1][2][3][4]
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References
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- ↑ Jensen R, et al. (1983) Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus. Proc Natl Acad Sci U S A 80(10):3035-9 SGD PMID 6344075
- ↑ Kostriken R, et al. (1983) A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell 35(1):167-74 SGD PMID 6313222
- ↑ Nasmyth K (1993) Regulating the HO endonuclease in yeast. Curr Opin Genet Dev 3(2):286-94 SGD PMID 8504254
- ↑ Strathern JN, et al. (1982) Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus. Cell 31(1):183-92 SGD PMID 6297747
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