Difference between revisions of "YOR109W"
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− | '''Description of YOR109W:''' | + | '''Description of YOR109W:''' Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains<ref name='S000073441'>Ha SA, et al. (2003) The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell 14(4):1319-33 {{SGDpaper|S000073441}} PMID 12686590</ref><ref name='S000059383'>Hughes WE, et al. (2000) Sac phosphatase domain proteins. Biochem J 350 Pt 2:337-52 {{SGDpaper|S000059383}} PMID 10947947</ref><ref name='S000059158'>Ooms LM, et al. (2000) The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Mol Cell Biol 20(24):9376-90 {{SGDpaper|S000059158}} PMID 11094088</ref><ref name='S000045780'>Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 |
{{SGDpaper|S000045780}} PMID 10224048</ref> | {{SGDpaper|S000045780}} PMID 10224048</ref> | ||
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Revision as of 07:21, 26 February 2009
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Systematic name | YOR109W |
Gene name | INP53 |
Aliases | SJL3, SOP2 |
Feature type | ORF, Verified |
Coordinates | Chr XV:525279..528602 |
Primary SGDID | S000005635 |
Description of YOR109W: Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains[1][2][3][4]
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References
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- ↑ Ha SA, et al. (2003) The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell 14(4):1319-33 SGD PMID 12686590
- ↑ Hughes WE, et al. (2000) Sac phosphatase domain proteins. Biochem J 350 Pt 2:337-52 SGD PMID 10947947
- ↑ Ooms LM, et al. (2000) The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Mol Cell Biol 20(24):9376-90 SGD PMID 11094088
- ↑ Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 SGD PMID 10224048
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