Difference between revisions of "YGR023W"

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'''Description of YGR023W:''' Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations<ref name='S000080345'>Vilella F, et al. (2005) Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress. J Biol Chem 280(10):9149-59 {{SGDpaper|S000080345}} PMID 15637049</ref><ref name='S000068904'>de Bettignies G, et al. (2001) Overactivation of the protein kinase C-signaling pathway suppresses the defects of cells lacking the Rho3/Rho4-GAP Rgd1p in Saccharomyces cerevisiae. Genetics 159(4):1435-48 {{SGDpaper|S000068904}} PMID 11779787</ref><ref name='S000052074'>Ketela T, et al. (1999) Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway. J Bacteriol 181(11):3330-40 {{SGDpaper|S000052074}} PMID 10348843</ref><ref name='S000048543'>Rajavel M, et al. (1999) Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae. Mol Cell Biol 19(6):3969-76
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'''Description of YGR023W:''' Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations<ref name='S000048543'>Rajavel M, et al. (1999) Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae. Mol Cell Biol 19(6):3969-76 {{SGDpaper|S000048543}} PMID 10330137</ref><ref name='S000052074'>Ketela T, et al. (1999) Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway. J Bacteriol 181(11):3330-40 {{SGDpaper|S000052074}} PMID 10348843</ref><ref name='S000068904'>de Bettignies G, et al. (2001) Overactivation of the protein kinase C-signaling pathway suppresses the defects of cells lacking the Rho3/Rho4-GAP Rgd1p in Saccharomyces cerevisiae. Genetics 159(4):1435-48 {{SGDpaper|S000068904}} PMID 11779787</ref><ref name='S000080345'>Vilella F, et al. (2005) Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress. J Biol Chem 280(10):9149-59
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  {{SGDpaper|S000080345}} PMID 15637049</ref>
 
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Revision as of 03:15, 19 December 2008

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Systematic name YGR023W
Gene name MTL1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:529268..530923
Primary SGDID S000003255


Description of YGR023W: Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations[1][2][3][4]




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References

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  1. Rajavel M, et al. (1999) Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae. Mol Cell Biol 19(6):3969-76 SGD PMID 10330137
  2. Ketela T, et al. (1999) Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway. J Bacteriol 181(11):3330-40 SGD PMID 10348843
  3. de Bettignies G, et al. (2001) Overactivation of the protein kinase C-signaling pathway suppresses the defects of cells lacking the Rho3/Rho4-GAP Rgd1p in Saccharomyces cerevisiae. Genetics 159(4):1435-48 SGD PMID 11779787
  4. Vilella F, et al. (2005) Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress. J Biol Chem 280(10):9149-59 SGD PMID 15637049

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