Difference between revisions of "YGR133W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003365 YGR133W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PEX4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PEX4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VII:756901..757452 | |nowrap| Chr VII:756901..757452 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003365 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YGR133W:''' Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis<ref name='S000080208'>Kragt A, et al. (2005) The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells. J Biol Chem 280(9):7867-74 {{SGDpaper|S000080208}} PMID 15632140</ref><ref name='S000073905'>Eckert JH and Johnsson N (2003) Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome. J Cell Sci 116(Pt 17):3623-34 {{SGDpaper|S000073905}} PMID 12876220</ref><ref name='S000054606'>Wiebel FF and Kunau WH (1992) The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes. Nature 359(6390):73-6 {{SGDpaper|S000054606}} PMID 1326082</ref><ref name='S000041712'>Erdmann R, et al. (1989) Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 86(14):5419-23 |
{{SGDpaper|S000041712}} PMID 2568633</ref> | {{SGDpaper|S000041712}} PMID 2568633</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR133W |
| Gene name | PEX4 |
| Aliases | PAS2, UBC10 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:756901..757452 |
| Primary SGDID | S000003365 |
Description of YGR133W: Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis[1][2][3][4]
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Community Commentary
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Protein Details
Other Protein Details
Other Topic: Homology
Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [5] [6]
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References
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- ↑ Kragt A, et al. (2005) The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells. J Biol Chem 280(9):7867-74 SGD PMID 15632140
- ↑ Eckert JH and Johnsson N (2003) Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome. J Cell Sci 116(Pt 17):3623-34 SGD PMID 12876220
- ↑ Wiebel FF and Kunau WH (1992) The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes. Nature 359(6390):73-6 SGD PMID 1326082
- ↑ Erdmann R, et al. (1989) Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 86(14):5419-23 SGD PMID 2568633
- ↑ Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 SGD PMID 16556314
- ↑ submitted by Toni Gabaldon on 2006-04-12
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