Difference between revisions of "YPL207W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006128 YPL207W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TYW1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TYW1 '' |
Latest revision as of 07:45, 23 January 2012
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Systematic name | YPL207W |
Gene name | TYW1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XVI:159909..162341 |
Primary SGDID | S000006128 |
Description of YPL207W: Iron-sulfer protein required for synthesis of Wybutosine modified tRNA; Wybutosine is a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; induction by Yap5p in response to iron provides protection from high iron toxicity; overexpression results in increased cellular iron[1][2]
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Contents
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References
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- ↑ Li L, et al. (2011) Yap5-regulated transcription of TYW1 protects yeast from high iron toxicity. J Biol Chem () SGD PMID 21917924
- ↑ Noma A and Suzuki T (2006) Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis. Nucleic Acids Symp Ser (Oxf) (50):65-6 SGD PMID 17150819
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