Difference between revisions of "YKL124W"

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'''Description of {{PAGENAME}}:''' Protein whose overexpression confers resistance to the growth inhibitor leflunomide; suppressor of shr3 mutation<ref name='S000055787'>Fujimura H (1998) Molecular cloning of Saccharomyces cerevisiae MLF4/SSH4 gene which confers the immunosuppressant leflunomide resistance. Biochem Biophys Res Commun 246(2):378-81
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'''Description of {{PAGENAME}}:''' Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane<ref name='S000120710'>Kota J, et al. (2007) Ssh4, Rcr2 and Rcr1 Affect Plasma Membrane Transporter Activity in Saccharomyces cerevisiae. Genetics ()
  {{SGDpaper|S000055787}} PMID 9610367</ref>
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  {{SGDpaper|S000120710}} PMID 17287526</ref>
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YKL124W
Gene name SSH4
Aliases MLF4
Feature type ORF, Verified
Coordinates Chr XI:210237..211976


Description of YKL124W: Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane[1]




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References

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  1. Kota J, et al. (2007) Ssh4, Rcr2 and Rcr1 Affect Plasma Membrane Transporter Activity in Saccharomyces cerevisiae. Genetics () SGD PMID 17287526

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