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Systematic name YKL124W
Gene name SSH4
Aliases MLF4
Feature type ORF, Verified
Coordinates Chr XI:210593..212332
Primary SGDID S000001607

Description of YKL124W: Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the multivesicular body; identified as a high-copy suppressor of a SHR3 deletion, increasing steady-state levels of amino acid permeases[1][2]


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  1. Kota J, et al. (2007) Ssh4, Rcr2 and Rcr1 Affect Plasma Membrane Transporter Activity in Saccharomyces cerevisiae. Genetics 175(4):1681-94 SGD PMID 17287526
  2. Leon S, et al. (2008) Ear1p and ssh4p are new adaptors of the ubiquitin ligase rsp5p for cargo ubiquitylation and sorting at multivesicular bodies. Mol Biol Cell 19(6):2379-88 SGD PMID 18367543

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