Difference between revisions of "YDR044W"
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
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Systematic name | YDR044W |
Gene name | HEM13 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IV:546640..547626 |
Description of YDR044W: Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)[1][2][3][4][5]
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References
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- ↑ Grandchamp B, et al. (1978) The mitochondrial localization of coproporphyrinogen III oxidase. Biochem J 176(1):97-102 SGD PMID 31872
- ↑ Urban-Grimal D and Labbe-Bois R (1981) Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis. Mol Gen Genet 183(1):85-92 SGD PMID 7035824
- ↑ Zagorec M, et al. (1988) Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase. J Biol Chem 263(20):9718-24 SGD PMID 2838478
- ↑ Keng T (1992) HAP1 and ROX1 form a regulatory pathway in the repression of HEM13 transcription in Saccharomyces cerevisiae. Mol Cell Biol 12(6):2616-23 SGD PMID 1588959
- ↑ Amillet JM, et al. (1995) Positive and negative elements involved in the differential regulation by heme and oxygen of the HEM13 gene (coproporphyrinogen oxidase) in Saccharomyces cerevisiae. Curr Genet 28(6):503-11 SGD PMID 8593679
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