Difference between revisions of "YBR011C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:257973..257110
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|nowrap| Chr II:257975..257112
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000215
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000215

Revision as of 13:05, 3 February 2011

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Systematic name YBR011C
Gene name IPP1
Aliases PPA1
Feature type ORF, Verified
Coordinates Chr II:257975..257112
Primary SGDID S000000215


Description of YBR011C: Cytoplasmic inorganic pyrophosphatase (PPase), homodimer that catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase[1][2][3]




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References

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  1. Kolakowski LF Jr, et al. (1988) Cloning, molecular characterization and chromosome localization of the inorganic pyrophosphatase (PPA) gene from S. cerevisiae. Nucleic Acids Res 16(22):10441-52 SGD PMID 2849749
  2. Lahti R, et al. (1990) Conservation of functional residues between yeast and E. coli inorganic pyrophosphatases. Biochim Biophys Acta 1038(3):338-45 SGD PMID 2160278
  3. Salminen A, et al. (2002) Modulation of dimer stability in yeast pyrophosphatase by mutations at the subunit interface and ligand binding to the active site. J Biol Chem 277(18):15465-71 SGD PMID 11854292

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