YBR011C
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Systematic name | YBR011C |
Gene name | IPP1 |
Aliases | PPA1 |
Feature type | ORF, Verified |
Coordinates | Chr II:257975..257112 |
Primary SGDID | S000000215 |
Description of YBR011C: Cytoplasmic inorganic pyrophosphatase (PPase), homodimer that catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase[1][2][3]
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References
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- ↑ Kolakowski LF Jr, et al. (1988) Cloning, molecular characterization and chromosome localization of the inorganic pyrophosphatase (PPA) gene from S. cerevisiae. Nucleic Acids Res 16(22):10441-52 SGD PMID 2849749
- ↑ Lahti R, et al. (1990) Conservation of functional residues between yeast and E. coli inorganic pyrophosphatases. Biochim Biophys Acta 1038(3):338-45 SGD PMID 2160278
- ↑ Salminen A, et al. (2002) Modulation of dimer stability in yeast pyrophosphatase by mutations at the subunit interface and ligand binding to the active site. J Biol Chem 277(18):15465-71 SGD PMID 11854292
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