Difference between revisions of "YDL194W"

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'''Description of YDL194W:''' Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4<ref name='S000043202'>Vagnoli P, et al. (1998) The C-terminal domain of Snf3p mediates glucose-responsive signal transduction in Saccharomyces cerevisiae. FEMS Microbiol Lett 160(1):31-6 {{SGDpaper|S000043202}} PMID 9495009</ref><ref name='S000045421'>Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69 {{SGDpaper|S000045421}} PMID 10477308</ref><ref name='S000046235'>Ozcan S, et al. (1996) Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci U S A 93(22):12428-32 {{SGDpaper|S000046235}} PMID 8901598</ref><ref name='S000048299'>Ko CH, et al. (1993) Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol Cell Biol 13(1):638-48
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'''Description of YDL194W:''' Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmembrane segments and a long C-terminal tail required for induction of hexose transporters; also senses fructose and mannose; similar to Rgt2p<ref name='S000043202'>Vagnoli P, et al. (1998) The C-terminal domain of Snf3p mediates glucose-responsive signal transduction in Saccharomyces cerevisiae. FEMS Microbiol Lett 160(1):31-6 {{SGDpaper|S000043202}} PMID 9495009</ref><ref name='S000046235'>Ozcan S, et al. (1996) Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci U S A 93(22):12428-32 {{SGDpaper|S000046235}} PMID 8901598</ref><ref name='S000048299'>Ko CH, et al. (1993) Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol Cell Biol 13(1):638-48 {{SGDpaper|S000048299}} PMID 8417358</ref><ref name='S000054594'>Ozcan S, et al. (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17(9):2566-73 {{SGDpaper|S000054594}} PMID 9564039</ref><ref name='S000132541'>Dietvorst J, et al. (2009) Amino acid residues involved in ligand preference of the Snf3 transporter-like sensor in Saccharomyces cerevisiae. Yeast ()
  {{SGDpaper|S000048299}} PMID 8417358</ref>
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  {{SGDpaper|S000132541}} PMID 20014043</ref>
 
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Revision as of 13:05, 4 January 2010

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Systematic name YDL194W
Gene name SNF3
Aliases
Feature type ORF, Verified
Coordinates Chr IV:111581..114235
Primary SGDID S000002353


Description of YDL194W: Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmembrane segments and a long C-terminal tail required for induction of hexose transporters; also senses fructose and mannose; similar to Rgt2p[1][2][3][4][5]




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Interactions

Regulatory

SNF3 expression is repressed by high levels of glucose, via the Snf1-Mig1 glucose repression pathway. [4] [6]





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References

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  1. Vagnoli P, et al. (1998) The C-terminal domain of Snf3p mediates glucose-responsive signal transduction in Saccharomyces cerevisiae. FEMS Microbiol Lett 160(1):31-6 SGD PMID 9495009
  2. Ozcan S, et al. (1996) Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci U S A 93(22):12428-32 SGD PMID 8901598
  3. Ko CH, et al. (1993) Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol Cell Biol 13(1):638-48 SGD PMID 8417358
  4. 4.0 4.1 Ozcan S, et al. (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17(9):2566-73 SGD PMID 9564039
  5. Dietvorst J, et al. (2009) Amino acid residues involved in ligand preference of the Snf3 transporter-like sensor in Saccharomyces cerevisiae. Yeast () SGD PMID 20014043
  6. submitted by Mark Johnston on 2003-03-11

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