Difference between revisions of "YJR050W"

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'''Description of YJR050W:''' Component of the spliceosome complex involved in pre-mRNA splicing, auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing; isy1 syf2 double mutation activates the spindle checkpoint, causing cell cycle arrest<ref name='S000071476'>Dahan O and Kupiec M (2002) Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint. Nucleic Acids Res 30(20):4361-70 {{SGDpaper|S000071476}} PMID 12384582</ref><ref name='S000069405'>Chen CH, et al. (2002) Functional and physical interactions between components of the Prp19p-associated complex. Nucleic Acids Res 30(4):1029-37 {{SGDpaper|S000069405}} PMID 11842115</ref><ref name='S000046470'>Chen CH, et al. (2001) Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p. J Biol Chem 276(1):488-94
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'''Description of YJR050W:''' Component of the spliceosome complex involved in pre-mRNA splicing, auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing; isy1 syf2 double mutation activates the spindle checkpoint, causing cell cycle arrest<ref name='S000046470'>Chen CH, et al. (2001) Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p. J Biol Chem 276(1):488-94 {{SGDpaper|S000046470}} PMID 11018040</ref><ref name='S000069405'>Chen CH, et al. (2002) Functional and physical interactions between components of the Prp19p-associated complex. Nucleic Acids Res 30(4):1029-37 {{SGDpaper|S000069405}} PMID 11842115</ref><ref name='S000071476'>Dahan O and Kupiec M (2002) Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint. Nucleic Acids Res 30(20):4361-70
  {{SGDpaper|S000046470}} PMID 11018040</ref>
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  {{SGDpaper|S000071476}} PMID 12384582</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YJR050W
Gene name ISY1
Aliases NTC30, UTR3
Feature type ORF, Verified
Coordinates Chr X:528689..529396
Primary SGDID S000003811


Description of YJR050W: Component of the spliceosome complex involved in pre-mRNA splicing, auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing; isy1 syf2 double mutation activates the spindle checkpoint, causing cell cycle arrest[1][2][3]




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References

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  1. Chen CH, et al. (2001) Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p. J Biol Chem 276(1):488-94 SGD PMID 11018040
  2. Chen CH, et al. (2002) Functional and physical interactions between components of the Prp19p-associated complex. Nucleic Acids Res 30(4):1029-37 SGD PMID 11842115
  3. Dahan O and Kupiec M (2002) Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint. Nucleic Acids Res 30(20):4361-70 SGD PMID 12384582

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