Difference between revisions of "YJR024C"
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| − | '''Description of YJR024C:''' 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant | + | '''Description of YJR024C:''' 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant<ref name='S000079733'>Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 {{SGDpaper|S000079733}} PMID 15292183</ref><ref name='S000076477'>Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 {{SGDpaper|S000076477}} PMID 15166135</ref><ref name='S000075217'>Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 {{SGDpaper|S000075217}} PMID 14665455</ref><ref name='S000122946'>Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4:9 {{SGDpaper|S000122946}} PMID 15102328</ref><ref name='S000127022'>Pirkov I, et al. (2008) A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J 275(16):4111-20 |
| − | {{SGDpaper| | + | {{SGDpaper|S000127022}} PMID 18625006</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YJR024C |
| Gene name | MDE1 |
| Aliases | |
| Feature type | ORF, Uncharacterized |
| Coordinates | Chr X:470956..470222 |
| Primary SGDID | S000003785 |
Description of YJR024C: 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant[1][2][3][4][5]
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References
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- ↑ Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 SGD PMID 15292183
- ↑ Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 SGD PMID 15166135
- ↑ Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 SGD PMID 14665455
- ↑ Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4:9 SGD PMID 15102328
- ↑ Pirkov I, et al. (2008) A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J 275(16):4111-20 SGD PMID 18625006
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