Difference between revisions of "YBR135W"

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'''Description of YBR135W:''' Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters<ref name='S000073499'>Morris MC, et al. (2003) Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature 423(6943):1009-13 {{SGDpaper|S000073499}} PMID 12827207</ref><ref name='S000062128'>Reynard GJ, et al. (2000) Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol Cell Biol 20(16):5858-64 {{SGDpaper|S000062128}} PMID 10913169</ref><ref name='S000054457'>Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 {{SGDpaper|S000054457}} PMID 10323869</ref><ref name='S000039561'>Hadwiger JA, et al. (1989) The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol Cell Biol 9(5):2034-41
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'''Description of YBR135W:''' Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters<ref name='S000039561'>Hadwiger JA, et al. (1989) The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol Cell Biol 9(5):2034-41 {{SGDpaper|S000039561}} PMID 2664468</ref><ref name='S000054457'>Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 {{SGDpaper|S000054457}} PMID 10323869</ref><ref name='S000062128'>Reynard GJ, et al. (2000) Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol Cell Biol 20(16):5858-64 {{SGDpaper|S000062128}} PMID 10913169</ref><ref name='S000073499'>Morris MC, et al. (2003) Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature 423(6943):1009-13
  {{SGDpaper|S000039561}} PMID 2664468</ref>
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  {{SGDpaper|S000073499}} PMID 12827207</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YBR135W
Gene name CKS1
Aliases
Feature type ORF, Verified
Coordinates Chr II:504848..505300
Primary SGDID S000000339


Description of YBR135W: Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters[1][2][3][4]




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References

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  1. Hadwiger JA, et al. (1989) The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol Cell Biol 9(5):2034-41 SGD PMID 2664468
  2. Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 SGD PMID 10323869
  3. Reynard GJ, et al. (2000) Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol Cell Biol 20(16):5858-64 SGD PMID 10913169
  4. Morris MC, et al. (2003) Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature 423(6943):1009-13 SGD PMID 12827207

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