Difference between revisions of "YOR197W"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| (10 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | <!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | ||
{{PageTop}} | {{PageTop}} | ||
| + | <protect> | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005723 YOR197W] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MCA1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MCA1 '' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''YCA1'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''YCA1, [MCA]'' |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XV: | + | |nowrap| Chr XV:717086..718384 |
|- | |- | ||
| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005723 |
|} | |} | ||
<br> | <br> | ||
| − | '''Description of | + | '''Description of YOR197W:''' Ca2+-activated cysteine protease; may cleave specific substrates during stress response; involved in regulation of apoptosis upon H2O2 treatment; contributes to clearance of insoluble protein aggregates during normal growth; may be involved in cell cycle progression; similar to mammalian caspases, but exists as a monomer due to an extra pair of anti-parallel beta-strands that form a continuous beta-sheet with the 6 caspase-common beta-strands, blocking potential dimerization<ref name='S000127360'>Lee RE, et al. (2008) A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics. PLoS ONE 3(8):e2956 {{SGDpaper|S000127360}} PMID 18698411</ref><ref name='S000135026'>Lee RE, et al. (2010) Metacaspase Yca1 is required for clearance of insoluble protein aggregates. Proc Natl Acad Sci U S A 107(30):13348-53 {{SGDpaper|S000135026}} PMID 20624963</ref><ref name='S000070033'>Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 {{SGDpaper|S000070033}} PMID 11983181</ref><ref name='S000150038'>Wong AH, et al. (2012) Crystal structure of the yeast metacaspase Yca1. J Biol Chem () |
| − | {{SGDpaper| | + | {{SGDpaper|S000150038}} PMID 22761449</ref> |
<br> | <br> | ||
<br> | <br> | ||
<br> | <br> | ||
<br> | <br> | ||
| − | + | <br> | |
| + | </protect> | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | |||
| + | |||
| + | |||
| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
| + | <!-- | ||
| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
| + | --> | ||
| + | |||
| + | |||
| + | |||
| + | <protect> | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
| + | </protect> | ||
Latest revision as of 13:05, 19 July 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOR197W |
| Gene name | MCA1 |
| Aliases | YCA1, [MCA] |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:717086..718384 |
| Primary SGDID | S000005723 |
Description of YOR197W: Ca2+-activated cysteine protease; may cleave specific substrates during stress response; involved in regulation of apoptosis upon H2O2 treatment; contributes to clearance of insoluble protein aggregates during normal growth; may be involved in cell cycle progression; similar to mammalian caspases, but exists as a monomer due to an extra pair of anti-parallel beta-strands that form a continuous beta-sheet with the 6 caspase-common beta-strands, blocking potential dimerization[1][2][3][4]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- ↑ Lee RE, et al. (2008) A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics. PLoS ONE 3(8):e2956 SGD PMID 18698411
- ↑ Lee RE, et al. (2010) Metacaspase Yca1 is required for clearance of insoluble protein aggregates. Proc Natl Acad Sci U S A 107(30):13348-53 SGD PMID 20624963
- ↑ Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 SGD PMID 11983181
- ↑ Wong AH, et al. (2012) Crystal structure of the yeast metacaspase Yca1. J Biol Chem () SGD PMID 22761449
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
