Difference between revisions of "YOR011W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005537 YOR011W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AUS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AUS1 '' | ||
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|nowrap| Chr XV:349679..353863 | |nowrap| Chr XV:349679..353863 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005537 |
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| − | '''Description of | + | '''Description of YOR011W:''' Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen<ref name='S000058997'>Alimardani P, et al. (2004) SUT1-promoted sterol uptake involves the ABC transporter Aus1 and the mannoprotein Dan1 whose synergistic action is sufficient for this process. Biochem J 381(Pt 1):195-202 {{SGDpaper|S000058997}} PMID 15035656</ref><ref name='S000141175'>Kohut P, et al. (2011) The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: Dehydroergosterol fluorescence study. Biochem Biophys Res Commun 404(1):233-8 {{SGDpaper|S000141175}} PMID 21110944</ref><ref name='S000145204'>Marek M, et al. (2011) The yeast plasma membrane ABC transporter Aus1: Purification, characterization and effect of lipids on its activity. J Biol Chem () {{SGDpaper|S000145204}} PMID 21521689</ref><ref name='S000071132'>Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72 |
{{SGDpaper|S000071132}} PMID 12077145</ref> | {{SGDpaper|S000071132}} PMID 12077145</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOR011W |
| Gene name | AUS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:349679..353863 |
| Primary SGDID | S000005537 |
Description of YOR011W: Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen[1][2][3][4]
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Community Commentary
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References
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- ↑ Alimardani P, et al. (2004) SUT1-promoted sterol uptake involves the ABC transporter Aus1 and the mannoprotein Dan1 whose synergistic action is sufficient for this process. Biochem J 381(Pt 1):195-202 SGD PMID 15035656
- ↑ Kohut P, et al. (2011) The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: Dehydroergosterol fluorescence study. Biochem Biophys Res Commun 404(1):233-8 SGD PMID 21110944
- ↑ Marek M, et al. (2011) The yeast plasma membrane ABC transporter Aus1: Purification, characterization and effect of lipids on its activity. J Biol Chem () SGD PMID 21521689
- ↑ Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72 SGD PMID 12077145
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