Difference between revisions of "YGR140W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003372 YGR140W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CBF2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CBF2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:767429..770299 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003372 |
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| − | '''Description of | + | '''Description of YGR140W:''' Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo<ref name='S000074756'>Espelin CW, et al. (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 {{SGDpaper|S000074756}} PMID 13679521</ref><ref name='S000044125'>Lechner J and Carbon J (1991) A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64(4):717-25 {{SGDpaper|S000044125}} PMID 1997204</ref><ref name='S000054823'>Yoon HJ and Carbon J (1995) Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol Cell Biol 15(9):4835-42 |
| − | {{SGDpaper| | + | {{SGDpaper|S000054823}} PMID 7651401</ref> |
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__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
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| + | '''Strain Background''': A364A/S288C<br> | ||
| + | Genetic interaction with MIF2 [[Category:Genetic Interactions with MIF2]]<br>'''Phenotype(s)''': Synthetic Lethal with MIF2 [[Category:Phenotype:Synthetic Lethal with MIF2]] | ||
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| + | at the time showed that MIF2 genetically interacts with an "established" centromere protein gene <ref name='S000053424'>Meluh PB and Koshland D (1995) Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol Biol Cell 6(7):793-807 {{SGDpaper|S000053424}} PMID 7579695</ref> <ref name = 'CAset3899-2003-03-17'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=3899 Pamela B. Meluh] on 2003-03-17</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR140W |
| Gene name | CBF2 |
| Aliases | CBF3A, CEP2, CSL5, CTF14, NDC10 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:767429..770299 |
| Primary SGDID | S000003372 |
Description of YGR140W: Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo[1][2][3]
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Community Commentary
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Interactions
Genetic
Strain Background: A364A/S288C
Genetic interaction with MIF2
Phenotype(s): Synthetic Lethal with MIF2
at the time showed that MIF2 genetically interacts with an "established" centromere protein gene [4] [5]
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References
See Help:References on how to add references
- ↑ Espelin CW, et al. (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 SGD PMID 13679521
- ↑ Lechner J and Carbon J (1991) A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64(4):717-25 SGD PMID 1997204
- ↑ Yoon HJ and Carbon J (1995) Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol Cell Biol 15(9):4835-42 SGD PMID 7651401
- ↑ Meluh PB and Koshland D (1995) Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol Biol Cell 6(7):793-807 SGD PMID 7579695
- ↑ submitted by Pamela B. Meluh on 2003-03-17
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
