Difference between revisions of "YGR112W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003344 YGR112W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SHY1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SHY1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:717358..718527 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003344 |
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| − | '''Description of | + | '''Description of YGR112W:''' Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome<ref name='S000069005'>Barrientos A, et al. (2002) Shy1p is necessary for full expression of mitochondrial COX1 in the yeast model of Leigh's syndrome. EMBO J 21(1-2):43-52 {{SGDpaper|S000069005}} PMID 11782424</ref><ref name='S000046510'>Mashkevich G, et al. (1997) SHY1, the yeast homolog of the mammalian SURF-1 gene, encodes a mitochondrial protein required for respiration. J Biol Chem 272(22):14356-64 {{SGDpaper|S000046510}} PMID 9162072</ref><ref name='S000124128'>Mick DU, et al. (2007) Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly. EMBO J 26(20):4347-58 |
| − | {{SGDpaper| | + | {{SGDpaper|S000124128}} PMID 17882259</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR112W |
| Gene name | SHY1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:717358..718527 |
| Primary SGDID | S000003344 |
Description of YGR112W: Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome[1][2][3]
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Community Commentary
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References
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- ↑ Barrientos A, et al. (2002) Shy1p is necessary for full expression of mitochondrial COX1 in the yeast model of Leigh's syndrome. EMBO J 21(1-2):43-52 SGD PMID 11782424
- ↑ Mashkevich G, et al. (1997) SHY1, the yeast homolog of the mammalian SURF-1 gene, encodes a mitochondrial protein required for respiration. J Biol Chem 272(22):14356-64 SGD PMID 9162072
- ↑ Mick DU, et al. (2007) Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly. EMBO J 26(20):4347-58 SGD PMID 17882259
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