Difference between revisions of "YOR359W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005886 YOR359W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VTS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VTS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XV: | + | |nowrap| Chr XV:1011189..1012760 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005886 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005886 | ||
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| − | '''Description of YOR359W:''' Post-transcriptional gene regulator, RNA-binding protein | + | '''Description of YOR359W:''' Post-transcriptional gene regulator, flap-structured DNA-binding and RNA-binding protein; shows genetic interactions with Vti1p, a v-SNARE involved in cis-Golgi membrane traffic; stimulates Dna2p endonuclease activity; contains a SAM domain<ref name='S000066006'>Dilcher M, et al. (2001) Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6. J Biol Chem 276(37):34537-44 {{SGDpaper|S000066006}} PMID 11445562</ref><ref name='S000132542'>Lee CH, et al. (2010) Involvement of Vts1, a structure-specific RNA-binding protein, in Okazaki fragment processing in yeast. Nucleic Acids Res 38(5):1583-95 {{SGDpaper|S000132542}} PMID 20007605</ref><ref name='S000114214'>Oberstrass FC, et al. (2006) Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol 13(2):160-7 |
| − | {{SGDpaper| | + | {{SGDpaper|S000114214}} PMID 16429156</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YOR359W |
| Gene name | VTS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:1011189..1012760 |
| Primary SGDID | S000005886 |
Description of YOR359W: Post-transcriptional gene regulator, flap-structured DNA-binding and RNA-binding protein; shows genetic interactions with Vti1p, a v-SNARE involved in cis-Golgi membrane traffic; stimulates Dna2p endonuclease activity; contains a SAM domain[1][2][3]
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Community Commentary
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Protein Details
Nucleic Acid Binding
YOR359W binds RNA Specific binding to an RNA stem-loop of CNGGN motif. Involved in CCR4 mediated deadnylation and degradation of targets. [4] [5]
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References
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- ↑ Dilcher M, et al. (2001) Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6. J Biol Chem 276(37):34537-44 SGD PMID 11445562
- ↑ Lee CH, et al. (2010) Involvement of Vts1, a structure-specific RNA-binding protein, in Okazaki fragment processing in yeast. Nucleic Acids Res 38(5):1583-95 SGD PMID 20007605
- ↑ Oberstrass FC, et al. (2006) Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol 13(2):160-7 SGD PMID 16429156
- ↑ Aviv T, et al. (2003) The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators. Nat Struct Biol 10(8):614-21 SGD PMID 12858164
- ↑ submitted by Tzvi Aviv on 2003-10-10
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