Difference between revisions of "YFL007W"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
 
(Automated import of articles)
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
{{PageTop}}
 
{{PageTop}}
 +
<protect>
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YFL007W YFL007W]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001887 YFL007W]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BLM10 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BLM10 ''
Line 12: Line 13:
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VI:123474..129905
+
|nowrap| Chr VI:123479..129910
 
|-
 
|-
|colspan = '3'|{{Don'tEditThisBox}}
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001887
 
|}
 
|}
 
<br>
 
<br>
'''Description of {{PAGENAME}}:''' Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200<ref name='S000114402'>Ustrell V, et al. (2002) PA200, a nuclear proteasome activator involved in DNA repair. EMBO J 21(13):3516-25 {{SGDpaper|S000114402}} PMID 12093752</ref><ref name='S000081108'>Schmidt M, et al. (2005) The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol 12(4):294-303 {{SGDpaper|S000081108}} PMID 15778719</ref><ref name='S000077319'>Doherty K, et al. (2004) Expression of the expanded YFL007w ORF and assignment of the gene name BLM10. Yeast 21(12):1021-3 {{SGDpaper|S000077319}} PMID 15449308</ref><ref name='S000076318'>Fehlker M, et al. (2003) Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly. EMBO Rep 4(10):959-63 {{SGDpaper|S000076318}} PMID 12973301</ref><ref name='S000069159'>Febres DE, et al. (2001) The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage. Cell Mol Biol (Noisy-le-grand) 47(7):1149-62
+
'''Description of YFL007W:''' Proteasome activator; binds the core proteasome and stimulates proteasome-mediated protein degradation by inducing gate opening; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200<ref name='S000147225'>Dange T, et al. (2011) Blm10 promotes proteasomal substrate turnover by an active gating mechanism. J Biol Chem () {{SGDpaper|S000147225}} PMID 22025621</ref><ref name='S000077319'>Doherty K, et al. (2004) Expression of the expanded YFL007w ORF and assignment of the gene name BLM10. Yeast 21(12):1021-3 {{SGDpaper|S000077319}} PMID 15449308</ref><ref name='S000069159'>Febres DE, et al. (2001) The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage. Cell Mol Biol (Noisy-le-grand) 47(7):1149-62 {{SGDpaper|S000069159}} PMID 11842813</ref><ref name='S000076318'>Fehlker M, et al. (2003) Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly. EMBO Rep 4(10):959-63 {{SGDpaper|S000076318}} PMID 12973301</ref><ref name='S000081108'>Schmidt M, et al. (2005) The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol 12(4):294-303 {{SGDpaper|S000081108}} PMID 15778719</ref><ref name='S000114402'>Ustrell V, et al. (2002) PA200, a nuclear proteasome activator involved in DNA repair. EMBO J 21(13):3516-25
  {{SGDpaper|S000069159}} PMID 11842813</ref>
+
  {{SGDpaper|S000114402}} PMID 12093752</ref>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
+
<br>
 +
</protect>
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
  
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
 +
 +
 +
 +
<protect>
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}
 +
</protect>

Latest revision as of 13:05, 10 February 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YFL007W
Gene name BLM10
Aliases YFL006W
Feature type ORF, Verified
Coordinates Chr VI:123479..129910
Primary SGDID S000001887


Description of YFL007W: Proteasome activator; binds the core proteasome and stimulates proteasome-mediated protein degradation by inducing gate opening; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200[1][2][3][4][5][6]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Dange T, et al. (2011) Blm10 promotes proteasomal substrate turnover by an active gating mechanism. J Biol Chem () SGD PMID 22025621
  2. Doherty K, et al. (2004) Expression of the expanded YFL007w ORF and assignment of the gene name BLM10. Yeast 21(12):1021-3 SGD PMID 15449308
  3. Febres DE, et al. (2001) The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage. Cell Mol Biol (Noisy-le-grand) 47(7):1149-62 SGD PMID 11842813
  4. Fehlker M, et al. (2003) Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly. EMBO Rep 4(10):959-63 SGD PMID 12973301
  5. Schmidt M, et al. (2005) The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol 12(4):294-303 SGD PMID 15778719
  6. Ustrell V, et al. (2002) PA200, a nuclear proteasome activator involved in DNA repair. EMBO J 21(13):3516-25 SGD PMID 12093752

See Help:Categories on how to add the wiki page for this gene to a Category </protect>