Difference between revisions of "YDR130C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
 
(7 intermediate revisions by the same user not shown)
Line 4: Line 4:
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002537 YDR130C]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002537 YDR130C]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''FIN1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''FIN1 ''
Line 13: Line 13:
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:716619..715744
+
|nowrap| Chr IV:716622..715747
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002537
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002537
 
|}
 
|}
 
<br>
 
<br>
'''Description of YDR130C:''' Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent<ref name='S000073072'>van Hemert MJ, et al. (2003) Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast. J Biol Chem 278(17):15049-55 {{SGDpaper|S000073072}} PMID 12551942</ref><ref name='S000070060'>Mayordomo I and Sanz P (2002) The Saccharomyces cerevisiae 14-3-3 protein Bmh2 is required for regulation of the phosphorylation status of Fin1, a novel intermediate filament protein. Biochem J 365(Pt 1):51-6 {{SGDpaper|S000070060}} PMID 11931638</ref><ref name='S000069577'>van Hemert MJ, et al. (2002) The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies. Proc Natl Acad Sci U S A 99(8):5390-3
+
'''Description of YDR130C:''' Spindle pole body-related intermediate filament protein; forms cell cycle-specific filaments between spindle pole bodies in dividing cells; localizes to poles and microtubules of spindle during anaphase and contributes to spindle stability; involved in Glc7p localization and regulation<ref name='S000132450'>Akiyoshi B, et al. (2009) Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev 23(24):2887-99 {{SGDpaper|S000132450}} PMID 19948764</ref><ref name='S000070060'>Mayordomo I and Sanz P (2002) The Saccharomyces cerevisiae 14-3-3 protein Bmh2 is required for regulation of the phosphorylation status of Fin1, a novel intermediate filament protein. Biochem J 365(Pt 1):51-6 {{SGDpaper|S000070060}} PMID 11931638</ref><ref name='S000124027'>Woodbury EL and Morgan DO (2007) The Role of Self-association in Fin1 Function on the Mitotic Spindle. J Biol Chem 282(44):32138-43 {{SGDpaper|S000124027}} PMID 17804403</ref><ref name='S000069577'>van Hemert MJ, et al. (2002) The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies. Proc Natl Acad Sci U S A 99(8):5390-3 {{SGDpaper|S000069577}} PMID 11929974</ref><ref name='S000073072'>van Hemert MJ, et al. (2003) Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast. J Biol Chem 278(17):15049-55
  {{SGDpaper|S000069577}} PMID 11929974</ref>
+
  {{SGDpaper|S000073072}} PMID 12551942</ref>
 
<br>
 
<br>
 
<br>
 
<br>

Latest revision as of 13:05, 8 June 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YDR130C
Gene name FIN1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:716622..715747
Primary SGDID S000002537


Description of YDR130C: Spindle pole body-related intermediate filament protein; forms cell cycle-specific filaments between spindle pole bodies in dividing cells; localizes to poles and microtubules of spindle during anaphase and contributes to spindle stability; involved in Glc7p localization and regulation[1][2][3][4][5]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Protein Details

Protein Modification

Modification(s): Glycosylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [6] [7]





<protect>

References

See Help:References on how to add references

  1. Akiyoshi B, et al. (2009) Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev 23(24):2887-99 SGD PMID 19948764
  2. Mayordomo I and Sanz P (2002) The Saccharomyces cerevisiae 14-3-3 protein Bmh2 is required for regulation of the phosphorylation status of Fin1, a novel intermediate filament protein. Biochem J 365(Pt 1):51-6 SGD PMID 11931638
  3. Woodbury EL and Morgan DO (2007) The Role of Self-association in Fin1 Function on the Mitotic Spindle. J Biol Chem 282(44):32138-43 SGD PMID 17804403
  4. van Hemert MJ, et al. (2002) The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies. Proc Natl Acad Sci U S A 99(8):5390-3 SGD PMID 11929974
  5. van Hemert MJ, et al. (2003) Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast. J Biol Chem 278(17):15049-55 SGD PMID 12551942
  6. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  7. submitted by Jeff Ubersax on 2004-01-21

See Help:Categories on how to add the wiki page for this gene to a Category </protect>