Difference between revisions of "YHR090C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001132 YHR090C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001132 YHR090C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YNG2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YNG2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VIII:284627..283779
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|nowrap| Chr VIII:284625..283777
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001132
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001132
 
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'''Description of YHR090C:''' Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1<ref name='S000073630'>Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 {{SGDpaper|S000073630}} PMID 12672825</ref><ref name='S000043268'>Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16
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'''Description of YHR090C:''' Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5<ref name='S000147081'>Chittuluru JR, et al. (2011) Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes.LID - 10.1038/nsmb.2128 [doi] Nat Struct Mol Biol () {{SGDpaper|S000147081}} PMID 21984211</ref><ref name='S000127778'>Gordon PM, et al. (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9:426 {{SGDpaper|S000127778}} PMID 18801192</ref><ref name='S000043268'>Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 {{SGDpaper|S000043268}} PMID 10805724</ref><ref name='S000073630'>Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5
  {{SGDpaper|S000043268}} PMID 10805724</ref>
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  {{SGDpaper|S000073630}} PMID 12672825</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YHR090C
Gene name YNG2
Aliases EAF4, NBN1
Feature type ORF, Verified
Coordinates Chr VIII:284625..283777
Primary SGDID S000001132


Description of YHR090C: Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5[1][2][3][4]




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References

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  1. Chittuluru JR, et al. (2011) Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes.LID - 10.1038/nsmb.2128 [doi] Nat Struct Mol Biol () SGD PMID 21984211
  2. Gordon PM, et al. (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9:426 SGD PMID 18801192
  3. Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 SGD PMID 10805724
  4. Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 SGD PMID 12672825

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