Difference between revisions of "YBR102C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000306 YBR102C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EXO84 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EXO84 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:447323..445062 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000306 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000306 | ||
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| − | '''Description of YBR102C:''' Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis | + | '''Description of YBR102C:''' Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis<ref name='S000069169'>Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 {{SGDpaper|S000069169}} PMID 11425851</ref><ref name='S000052580'>Guo W, et al. (1999) Exo84p is an exocyst protein essential for secretion. J Biol Chem 274(33):23558-64 {{SGDpaper|S000052580}} PMID 10438536</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074306}} PMID 14574415</ref> |
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR102C |
| Gene name | EXO84 |
| Aliases | USA3 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:447323..445062 |
| Primary SGDID | S000000306 |
Description of YBR102C: Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis[1][2][3]
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Contents
Community Commentary
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Interactions
Two Hybrid
Two Hybrid interaction with Prp8
Prp8 binds to C-terminus of Exo84 [4] [5]
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [6]
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References
See Help:References on how to add references
- ↑ Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 SGD PMID 11425851
- ↑ Guo W, et al. (1999) Exo84p is an exocyst protein essential for secretion. J Biol Chem 274(33):23558-64 SGD PMID 10438536
- ↑ 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
SGD PMID 14574415 Cite error: Invalid
<ref>tag; name "S000074306" defined multiple times with different content - ↑ Kuhn AN and Brow DA (2000) Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155(4):1667-82 SGD PMID 10924465
- ↑ submitted by Richard Grainger on 2003-04-11
- ↑ submitted by Jeff Ubersax on 2004-01-21
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