Difference between revisions of "YBL052C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000148 YBL052C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SAS3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SAS3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:121874..119379 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000148 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000148 | ||
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| − | '''Description of YBL052C:''' Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; | + | '''Description of YBL052C:''' Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5 double mutation is lethal<ref name='S000066268'>Howe L, et al. (2001) Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev 15(23):3144-54 {{SGDpaper|S000066268}} PMID 11731478</ref><ref name='S000050029'>John S, et al. (2000) The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev 14(10):1196-208 {{SGDpaper|S000050029}} PMID 10817755</ref><ref name='S000047845'>Reifsnyder C, et al. (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet 14(1):42-9 {{SGDpaper|S000047845}} PMID 8782818</ref><ref name='S000136872'>Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83 |
| − | {{SGDpaper| | + | {{SGDpaper|S000136872}} PMID 20850176</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YBL052C |
| Gene name | SAS3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:121874..119379 |
| Primary SGDID | S000000148 |
Description of YBL052C: Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5 double mutation is lethal[1][2][3][4]
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References
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- ↑ Howe L, et al. (2001) Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev 15(23):3144-54 SGD PMID 11731478
- ↑ John S, et al. (2000) The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev 14(10):1196-208 SGD PMID 10817755
- ↑ Reifsnyder C, et al. (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet 14(1):42-9 SGD PMID 8782818
- ↑ Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83 SGD PMID 20850176
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