Difference between revisions of "tS(CGA)C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006730 tS(CGA)C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SUP61 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SUP61 '' | ||
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− | '''Description of tS(CGA)C:''' tRNA-Ser; i6A37 modification is catalyzed by Mod5p<ref name='S000146670'>Lamichhane TN, et al. (2011) Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases. RNA () | + | '''Description of tS(CGA)C:''' Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis; i6A37 modification is catalyzed by Mod5p; can mutate to suppress amber or ochre nonsense mutations; suppressor mutant alleles are recessive lethal and can only be maintained when an additional wild-type copy of the gene is present, because SUP61 encodes the only tRNA species that can decode UCG codons<ref name='S000116419'>Brandriss MC, et al. (1975) Recessive lethal amber suppressors in yeast. Genetics 79(4):551-60 {{SGDpaper|S000116419}} PMID 1093932</ref><ref name='S000147623'>Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 {{SGDpaper|S000147623}} PMID 18984615</ref><ref name='S000048669'>Etcheverry T, et al. (1982) Recessive lethality of yeast strains carrying the SUP61 suppressor results from loss of a transfer RNA with a unique decoding function. J Mol Biol 158(4):599-618 {{SGDpaper|S000048669}} PMID 6750138</ref><ref name='S000146670'>Lamichhane TN, et al. (2011) Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases. RNA () |
{{SGDpaper|S000146670}} PMID 21873461</ref> | {{SGDpaper|S000146670}} PMID 21873461</ref> | ||
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Latest revision as of 14:05, 6 August 2012
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Systematic name | tS(CGA)C |
Gene name | SUP61 |
Aliases | |
Feature type | tRNA |
Coordinates | Chr III:227942..228042 |
Primary SGDID | S000006730 |
Description of tS(CGA)C: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis; i6A37 modification is catalyzed by Mod5p; can mutate to suppress amber or ochre nonsense mutations; suppressor mutant alleles are recessive lethal and can only be maintained when an additional wild-type copy of the gene is present, because SUP61 encodes the only tRNA species that can decode UCG codons[1][2][3][4]
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References
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- ↑ Brandriss MC, et al. (1975) Recessive lethal amber suppressors in yeast. Genetics 79(4):551-60 SGD PMID 1093932
- ↑ Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 SGD PMID 18984615
- ↑ Etcheverry T, et al. (1982) Recessive lethality of yeast strains carrying the SUP61 suppressor results from loss of a transfer RNA with a unique decoding function. J Mol Biol 158(4):599-618 SGD PMID 6750138
- ↑ Lamichhane TN, et al. (2011) Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases. RNA () SGD PMID 21873461
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