tS(CGA)C
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| Systematic name | tS(CGA)C |
| Gene name | SUP61 |
| Aliases | |
| Feature type | tRNA |
| Coordinates | Chr III:227942..228042 |
| Primary SGDID | S000006730 |
Description of tS(CGA)C: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis; i6A37 modification is catalyzed by Mod5p; can mutate to suppress amber or ochre nonsense mutations; suppressor mutant alleles are recessive lethal and can only be maintained when an additional wild-type copy of the gene is present, because SUP61 encodes the only tRNA species that can decode UCG codons[1][2][3][4]
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References
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- ↑ Brandriss MC, et al. (1975) Recessive lethal amber suppressors in yeast. Genetics 79(4):551-60 SGD PMID 1093932
- ↑ Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 SGD PMID 18984615
- ↑ Etcheverry T, et al. (1982) Recessive lethality of yeast strains carrying the SUP61 suppressor results from loss of a transfer RNA with a unique decoding function. J Mol Biol 158(4):599-618 SGD PMID 6750138
- ↑ Lamichhane TN, et al. (2011) Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases. RNA () SGD PMID 21873461
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