Difference between revisions of "YBR156C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBR156C YBR156C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000360 YBR156C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SLI15 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SLI15 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:553194..551098
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|nowrap| Chr II:553200..551104
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000360
 
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'''Description of {{PAGENAME}}:''' Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase<ref name='S000080225'>D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95 {{SGDpaper|S000080225}} PMID 15520278</ref><ref name='S000078515'>Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 {{SGDpaper|S000078515}} PMID 12566427</ref><ref name='S000069415'>Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29 {{SGDpaper|S000069415}} PMID 11853667</ref><ref name='S000068910'>Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 {{SGDpaper|S000068910}} PMID 11731476</ref><ref name='S000041165'>Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94
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'''Description of YBR156C:''' Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly<ref name='S000068910'>Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 {{SGDpaper|S000068910}} PMID 11731476</ref><ref name='S000078515'>Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 {{SGDpaper|S000078515}} PMID 12566427</ref><ref name='S000080225'>D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95 {{SGDpaper|S000080225}} PMID 15520278</ref><ref name='S000041165'>Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94 {{SGDpaper|S000041165}} PMID 10385519</ref><ref name='S000129008'>Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84 {{SGDpaper|S000129008}} PMID 19158380</ref><ref name='S000069415'>Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29
  {{SGDpaper|S000041165}} PMID 10385519</ref>
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  {{SGDpaper|S000069415}} PMID 11853667</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YBR156C
Gene name SLI15
Aliases
Feature type ORF, Verified
Coordinates Chr II:553200..551104
Primary SGDID S000000360


Description of YBR156C: Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly[1][2][3][4][5][6]




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References

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  1. Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 SGD PMID 11731476
  2. Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 SGD PMID 12566427
  3. D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95 SGD PMID 15520278
  4. Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94 SGD PMID 10385519
  5. Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84 SGD PMID 19158380
  6. Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29 SGD PMID 11853667

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